Thursday, December 6, 2012

The two week wait, with added agony

I really don't know where to start with this post, so I'll just come straight out with it.  We have just completed what will have been our first and only IVF cycle, and I am now two days post embryo transfer.  We decided to do it more as a closure thing than anything else.  We both felt that if we didn't explore every avenue then we would look back with regrets.

So, at the ripe old age of 43, I went down a road I thought I never would.  Our RE was starkly honest about our chances of success - somewhere around 5% I think.  I'll write more later about our protocol and false starts along the way, but once we finally got going, my meds were as follows:

Gonal F 300, increased to 450 on CD8 (I think it was CD8) once per day
Luveris once per day
Clexane once per day
Buserilin injections, morning and night
Prednisolone 25mg per day

To be honest at the outset I was only going through the motions.  To me it was a box ticking exercise (pardon the pun), one more thing to say we tried.  I imagined my ancient ovaries might struggle to make three or four eggs.  It turned out that I vastly underestimated them.  At my CD7 scan I had 10 follicles, at CD 9, 11 follicles, at CD 12, 14 follicles and at CD13 they thought possibly 15 follicles.  Oh my poor aching ovaries, but boy was I proud of them!

My egg collection went really well.  The morphine cocktail sent me off into the most blissful sleep I had had in months, and a total of 13 eggs were retrieved.  We really could not believe it.  13 eggs from my 43 year old ovaries.  The following day we got the call to say that out of 13, 8 were mature, and six fertilised by ICSI.  That was last Friday afternoon, and we were told that we would not hear anymore from the clinic until Monday afternoon.

I had intended going back into work that day to clear my desk, but wisely decided against it.  Monday seemed to go on forever.  I swung between wild optimism and depths of dispair.  What if none survived and it was game over?  At 4.15pm the call came.  At 4 days post retrieval, five out of six of our embryos were still hanging in there.  We were to come back to the clinic at 2pm the following day.  The embryologist would check our little crop in the morning, but if all was well we would not hear from them.

So no phone call came and off we set for Dublin once more.  I struggled with a full bladder, and had to go to the bathroom and start refilling.  I got gowned up and we went down to the transfer room.  The embryologist came in and told us that although we still had five embryos, two had slowed down in development so we were now down to three.  The two best ones were being transferred and if the remaining one still looked good the following day, they would call us to let us know they would freeze.  If they didn't call, we could take it that it was not fit for freezing.

Then it was time to get into the stirrups and get these embryos into their new home.  It all went easier than I had expected.  I didn't have to have my bladder full to bursting which I had been dreading, and the whole procedure didn't last more than five minutes.  The doctor and nurses were really lovely and put us at our ease.  An hour or so later we were ready for the road home.  I reclined the passenger seat, snuggled up under a blanket and got some much needed sleep.

Since then I have been putting the feet up.  We didn't get that call from the embryologist, so that means we don't have a backup frozen embryo.  But we do have two little blastocysts on board.  My mood is all over the place.  Today I am extremely weepy, only able to think of how hard it will be when I get a negative test.  Other times I allow myself to think it might work.  I have to keep reminding myself of how far we have come and how much our expectations have been exceeded so far.  So who knows?  In ten days time all will be revealed....

17 comments:

  1. Oh wow!! I'm so so happy you gave this a go! If you have been to the clinic I think you have been, you would have got the best care possible. Your blasts are now deeply snuggled in and I'll be very proud of you if you'l manage to wait the full 12 days recommended! I always tested (with a FRER) at 9 or 10dp5dt, plenty of time to see if it worked. I'm here for you if you need a chat, the 2ww are awful for everyone, and the mood swings totally normal too! Love, Fran

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    1. Hi Fran, if it's the clinic in Dublin 6 beside the Honda showrooms then you're spot on ;-) I was extremely impressed with their level of care. We really felt that we were in safe hands from the start.

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  2. Blimey, Jane! You HAVE been busy! Will be thinking of you.

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  3. Good luck, good luck, oh, so many hugs and best wishes and crossing of fingers and holding of hands.

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  4. Delurking to wish you lots and lots of luck.

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    1. Ooh I love when somebody delurks! Thanks Sheila!

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  5. Thanks everyone for your much needed and appreciated support! I wrote a long comment and my phone eated it. Grrrr.

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  6. Wow! Wow! Jane! that's great news. Much much luck!

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  7. Here from LFCA --- wishing you the best of luck with this cycle.

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  8. Here from LFCA too-- my last transfer was the day before I turned 43, and I got pregnant with Della-- so my fingers are SO CROSSED FOR YOU. Here's hoping for wonderful,stat-busting success.

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  9. Hi there, here from LFCA. Just wanted to say that I got pregnant at 43 through IVF, and I now have a super-happy baby. So yes, it's possible. You have a better chance than winning Powerball... fingers crossed for you!

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  10. Also from LFCA-fingers crossed for you!

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